Immunoassay cross-reactivity and aderol

J Anal Toxicol. 2007 May;31(4):208-13. Matrix effect and cross-reactivity of select amphetamine-type substances, designer analogues, and putrefactive amines using the Bio-Quant direct ELISA presumptive assays for amphetamine and methamphetamine. Apollonio LG(1), Whittall IR, Pianca DJ, Kyd JM, Maher WA. Given the structural similarity between agents, such as ephedrine and amphetamine, this finding was not unexpected, and such cross-reactivity has been previously. . Of these patients, 36% had false-positive urine results for amphetamines using the EMIT II Plus monoclonal amphetamine/ methamphetamine immunoassay. Cross reactivity of structrally similar substances can be a problem associated with immunoassay methods, which can result in false. Positive for Barbiturates (BAR ). Amoxicillin or Amoxycillin. Amoxil, Amoram, Augmentin,. Heliclear. Non- reactive. Amphetamine/Methamphetamine AMP; Adderall, Dexedrine,. Benzedrine,. Clin Toxicol (Phila). 2013 Feb;51(2):83-91. doi: 10.3109/15563650.2013.768344. Cross-reactivity studies and predictive modeling of "Bath Salts" and other amphetamine-type stimulants with amphetamine screening immunoassays. Petrie M(1), Lynch KL, Ekins S, Chang JS, Goetz RJ, Wu AH, Krasowski MD. With high consumption, the alcohol content could cause a positive alcohol screen but it should not cause immunoassays for DOA to be falsely positive at normal doses (Note: always refer to your assay's cross-reactivity specs). My patient is taking Adderall for ADHD/ADD. Why are they positive for amphetamine? The drug . Oct 16, 2012 . Key Points about Immunoassays. – Good & Bad Cross-reactivity (sensitivity). – Can be different with different vendors. Cross-reactivity. Amphetamine. Methamphetamine. Bupropion. Morphine . Amphetamine Assay Cross-reactivity. Trade Name. Generic Name Immunoassay. LC-MS. Adderall, Dexedrine,. Dextrostat, Vyvanse d-amphetamine. +. +AMPH. Desoxyn methamphetamine. +. +METH. +AMPH. Anipryl, Zelapar. Selegiline. +. + METH. +AMPH. Various Rx Drugs. Phentermine,. Bupropion,. Trazadone . Using molecular similarity to highlight the challenges of routine immunoassay- based drug of abuse/toxicology screening in emergency medicine. Matthew D KrasowskiEmail author,; Anthony F Pizon,; Mohamed G Siam,; Spiros Giannoutsos,; Manisha Iyer and; Sean Ekins. BMC Emergency Medicine20099:5. Oct 1, 2009 . For example, Adderall contains a mixed amphetamine salt widely prescribed as a psychostimulant medication for. cross-reactivity with different opiate-screening assays, and there is also a specific immunoassay which recognizes the presence of oxycodone in urine — but taking codeine or morphine .