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KEY C W D21⁄2W D5W D10W D5/1⁄4NS D5/1⁄2NS D5NS NS 1⁄2NS R LR D5R D5LR ؍ Compatible* Dextran 6%/D5W/NS ؍ Dextran 6% in D5W or normal saline ؍ Compatible in water not NS 1 ؍ 2 ⁄2% Dextrose in water Fruc 10%/ W/NS ؍ Fructose 10% in water or normal saline ؍ 5% Dextrose in water ؍ 10% . UNASYN should be administered by slow intravenous injection over at least 10– 15 minutes or can also be delivered in greater dilutions with 50–100 mL of a compatible diluent as an intravenous infusion over 15–30 minutes. The recommended adult dosage of UNASYN is 1.5 g (1 g ampicillin as the sodium salt plus 0.5. The most discussed change in parenteral nutrition compatibility within the last two years was with ceftriaxone. In the summer of 2007, Roche Laboratories updated their prescribing information for Rocephin® (ceftriaxone sodium) to include a contraindication for the co-administration of ceftriaxone with calcium- containing . Vials: Further dilute vials with compatible IV solution (i.e., 0.9% Sodium Chloride Injection, 5% Dextrose Injection, Lactated Ringer's Injection) to a usual concentration of 3—45 mg/mL of ampicillin; sulbactam (i.e., 2—30 mg/mL ampicillin and 1—15 mg/mL of sulbactam). Piggyback bottles: Following reconstitution, no further . DIRECTIONS FOR USE General Dissolution Procedures. Ampicillin and Sulbactam for Injection sterile powder for intravenous and intramuscular use may be reconstituted with any of the compatible diluents described in this insert. Solutions should be allowed to stand after dissolution to allow any foaming to dissipate in . For IV administration, the dose can be given by slow intravenous injection over at least 10–15 minutes or can also be delivered in greater dilutions with 50–100 mL of a compatible diluent as an intravenous infusion over 15–30 minutes. UNASYN may be administered by deep intramuscular injection. (see DIRECTIONS FOR . UNASYN sterile powder for intravenous and intramuscular use may be reconstituted with any of the compatible diluents described in this insert.. Initially, the vials may be reconstituted with Sterile Water for Injection to yield solutions containing 375 mg UNASYN per mL (250 mg ampicillin/125 mg sulbactam per mL). Disclaimer: This IV Drug Compatibility Chart is provided as a quick reference, however since information is subject to change it is advised that you check with a pharmacist for recommendations as well as product information to check for any changes or additional incompatibilities. Key: • = Compatible. • = Incompatible.